4 Chao Phraya Abhaibhubejhr Hospital Foundation, Prachinburi, Thailand
To determine the effect of SIRT3 on epigenetic regulation beyond HSCs, we performed single-nuclei ATAC-sequencing of lineage-negative cells from 2-year-old Mx1-Cre and Mx1-T3 mice using the 10x Genomics Chromium platform
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As described here in the Experimental section in Methods and Results, it has been possible to obtain some estimate of the limiting solubility of niclosamide from nanodrop UV/Vis by evaluating two noisy scans, i.e., one for the blank buffer and one for the niclosamide solution at pH 3.66, where the niclosamide solubility is expected to be its absolute lowest
Palmer SC, Tendal B, Mustafa RA, Vandvik PO, Li S, Hao Q, et al
PMCID: PMC6658305